Activation of Melanocortin 1 Receptor Attenuates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage viathe Suppression of Neuroinflammation through AMPK/TBK1/NF-κB Pathway in Rats

Neuroinflammation plays a vital role in early brain injury (EBI) following subarachnoid hemorrhage (SAH). The hypothesis of this study was that activation of melanocortin 1 receptor (MC1R) with BMS-470539 attenuates EBI by suppression of neuroinflammation after SAH. We utilized BMS-470539, MSG-606,...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Xu, Weilin, Mo, Jun, Ocak, Umut, Travis, Zachary D., Enkhjargal, Budbazar, Zhang, Tongyu, Wu, Pei, Peng, Jianhua, Li, Tao, Zuo, Yuchun, Shao, Anwen, Tang, Jiping, Zhang, Jianmin, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007470/
https://ncbi.nlm.nih.gov/pubmed/31486022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00772-x
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