Activation of Melanocortin 1 Receptor Attenuates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage viathe Suppression of Neuroinflammation through AMPK/TBK1/NF-κB Pathway in Rats

Neuroinflammation plays a vital role in early brain injury (EBI) following subarachnoid hemorrhage (SAH). The hypothesis of this study was that activation of melanocortin 1 receptor (MC1R) with BMS-470539 attenuates EBI by suppression of neuroinflammation after SAH. We utilized BMS-470539, MSG-606,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neurotherapeutics
Hlavní autoři: Xu, Weilin, Mo, Jun, Ocak, Umut, Travis, Zachary D., Enkhjargal, Budbazar, Zhang, Tongyu, Wu, Pei, Peng, Jianhua, Li, Tao, Zuo, Yuchun, Shao, Anwen, Tang, Jiping, Zhang, Jianmin, Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007470/
https://ncbi.nlm.nih.gov/pubmed/31486022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00772-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky