Transgenic expression of human CD47 reduces phagocytosis of porcine endothelial cells and podocytes by baboon and human macrophages

Our initial studies utilizing a 1,3-galactosyltransferase (GalTKO) knockout pig-to-baboon renal transplant model demonstrated that the early development of nephrotic syndrome has been a significant obstacle to the long-term survival of baboon recipients. We have recently documented that sphingomyeli...

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Gepubliceerd in:Xenotransplantation
Hoofdauteurs: Nomura, Shunichiro, Ariyoshi, Yuichi, Watanabe, Hironosuke, Pomposelli, Thomas, Takeuchi, Kazuhiro, Garcia, Gabriela, Tasaki, Masayuki, Ayares, David, Sykes, Megan, Sachs, David, Johnson, Richard, Yamada, Kazuhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007337/
https://ncbi.nlm.nih.gov/pubmed/31495971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12549
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