Protection of Pancreatic Islets Using Theranostic Silencing Nanoparticles in a Baboon Model of Islet Transplantation

The long-term success of pancreatic islet transplantation (Tx) as a cure for type 1 diabetes remains limited. Islet loss after Tx related to apoptosis, inflammation, and other factors continues to limit Tx efficacy. In this project, we demonstrate a novel approach aimed at protecting islets before T...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Pomposelli, Thomas, Wang, Ping, Takeuchi, Kazuhiro, Miyake, Katsunori, Ariyoshi, Yuichi, Watanabe, Hironosuke, Chen, Xiaojuan, Shimizu, Akira, Robertson, Neil, Yamada, Kazuhiko, Moore, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576559/
https://ncbi.nlm.nih.gov/pubmed/32855170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0517
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