The Efficacy of Mitotane in Human Primary Adrenocortical Carcinoma Cultures

CONTEXT: Patients with adrenocortical carcinoma (ACC) often fail mitotane treatment and deal with severe toxicity, marking the relevance of predictive parameters for treatment outcome. OBJECTIVE: Determine the effects of mitotane in primary ACC cultures, and correlate sensitivity with patient and tu...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: van Koetsveld, Peter M, Creemers, Sara G, Dogan, Fadime, Franssen, Gaston J H, de Herder, Wouter W, Feelders, Richard A, Hofland, Leo J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006231/
https://ncbi.nlm.nih.gov/pubmed/31586196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz001
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