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TBC1D9 regulates TBK1 activation through Ca(2+) signaling in selective autophagy
Invading microbial pathogens can be eliminated selectively by xenophagy. Ubiquitin-mediated autophagy receptors are phosphorylated by TANK-binding kinase 1 (TBK1) and recruited to ubiquitinated bacteria to facilitate autophagosome formation during xenophagy, but the molecular mechanism underlying TB...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7005872/ https://ncbi.nlm.nih.gov/pubmed/32034138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14533-4 |
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