NLRX1 Negatively Regulates Group A Streptococcus Invasion and Autophagy Induction by Interacting With the Beclin 1–UVRAG Complex

Group A Streptococcus (GAS) can invade epithelial cells; however, these bacteria are targeted and eventually destroyed by autophagy. Members of the Nod-like receptor (NLR) family are thought to be critical for the autophagic response to invasive bacteria. However, the intracellular sensors within ho...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Aikawa, Chihiro, Nakajima, Shintaro, Karimine, Miho, Nozawa, Takashi, Minowa-Nozawa, Atsuko, Toh, Hirotaka, Yamada, Shunsuke, Nakagawa, Ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246980/
https://ncbi.nlm.nih.gov/pubmed/30488027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00403
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