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Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy

Autophagy selectively targets invading bacteria to defend cells, whereas bacterial pathogens counteract autophagy to survive in cells. The initiation of canonical autophagy involves the PIK3C3 complex, but autophagy targeting Group A Streptococcus (GAS) is PIK3C3-independent. We report that GAS infe...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Toh, Hirotaka, Nozawa, Takashi, Minowa-Nozawa, Atsuko, Hikichi, Miyako, Nakajima, Shintaro, Aikawa, Chihiro, Nakagawa, Ichiro
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984453/
https://ncbi.nlm.nih.gov/pubmed/31177902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1628539
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