“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Antigen-specific redirection of immune effector cells with chimeric antigen receptors (CARs) demonstrated high therapeutic potential for targeting cancers of different origins. Beside CAR-T cells, natural killer (NK) cells represent promising alternative effectors that can be combined with CAR techn...

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Publicado no:Sci Rep
Main Authors: Mitwasi, Nicola, Feldmann, Anja, Arndt, Claudia, Koristka, Stefanie, Berndt, Nicole, Jureczek, Justyna, Loureiro, Liliana R., Bergmann, Ralf, Máthé, Domokos, Hegedüs, Nikolett, Kovács, Tibor, Zhang, Congcong, Oberoi, Pranav, Jäger, Elke, Seliger, Barbara, Rössig, Claudia, Temme, Achim, Eitler, Jiri, Tonn, Torsten, Schmitz, Marc, Hassel, Jessica C., Jäger, Dirk, Wels, Winfried S., Bachmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005792/
https://ncbi.nlm.nih.gov/pubmed/32034289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59082-4
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