Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Despite intensive research and constant medical progress, sepsis remains one of the most urgent unmet medical needs of today. Most studies have been focused on the inflammatory component of the disease; however, recent advances support the notion that sepsis is accompanied by extensive metabolic per...

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Veröffentlicht in:EMBO Mol Med
Hauptverfasser: Van Wyngene, Lise, Vanderhaeghen, Tineke, Timmermans, Steven, Vandewalle, Jolien, Van Looveren, Kelly, Souffriau, Jolien, Wallaeys, Charlotte, Eggermont, Melanie, Ernst, Sam, Van Hamme, Evelien, Gonçalves, Amanda, Eelen, Guy, Remmerie, Anneleen, Scott, Charlotte L, Rombouts, Caroline, Vanhaecke, Lynn, De Bus, Liesbet, Decruyenaere, Johan, Carmeliet, Peter, Libert, Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005534/
https://ncbi.nlm.nih.gov/pubmed/31916705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911319
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