Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates

Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and produce a limited region of therapeutic effect....

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Ther Methods Clin Dev
Asıl Yazarlar: Yiu, Glenn, Chung, Sook Hyun, Mollhoff, Iris N., Nguyen, Uyen Tu, Thomasy, Sara M., Yoo, Jesse, Taraborelli, Donna, Noronha, Glenn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005511/
https://ncbi.nlm.nih.gov/pubmed/32055646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.01.002
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller