Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates

Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and produce a limited region of therapeutic effect....

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Ther Methods Clin Dev
Autores principales: Yiu, Glenn, Chung, Sook Hyun, Mollhoff, Iris N., Nguyen, Uyen Tu, Thomasy, Sara M., Yoo, Jesse, Taraborelli, Donna, Noronha, Glenn
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005511/
https://ncbi.nlm.nih.gov/pubmed/32055646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.01.002
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares