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Perpendicular alignment of lymphatic endothelial cells in response to spatial gradients in wall shear stress

One-way valves in the lymphatic system form from lymphatic endothelial cells (LECs) during embryonic development and are required for efficient tissue drainage. Although fluid flow is thought to guide both valve formation and maintenance, how this occurs at a mechanistic level remains incompletely u...

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Détails bibliographiques
Publié dans:Commun Biol
Auteurs principaux: Michalaki, Eleftheria, Surya, Vinay N., Fuller, Gerald G., Dunn, Alexander R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005002/
https://ncbi.nlm.nih.gov/pubmed/32029852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0732-8
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