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Perpendicular alignment of lymphatic endothelial cells in response to spatial gradients in wall shear stress

One-way valves in the lymphatic system form from lymphatic endothelial cells (LECs) during embryonic development and are required for efficient tissue drainage. Although fluid flow is thought to guide both valve formation and maintenance, how this occurs at a mechanistic level remains incompletely u...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Michalaki, Eleftheria, Surya, Vinay N., Fuller, Gerald G., Dunn, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005002/
https://ncbi.nlm.nih.gov/pubmed/32029852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0732-8
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