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Perpendicular alignment of lymphatic endothelial cells in response to spatial gradients in wall shear stress

One-way valves in the lymphatic system form from lymphatic endothelial cells (LECs) during embryonic development and are required for efficient tissue drainage. Although fluid flow is thought to guide both valve formation and maintenance, how this occurs at a mechanistic level remains incompletely u...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Commun Biol
Hauptverfasser: Michalaki, Eleftheria, Surya, Vinay N., Fuller, Gerald G., Dunn, Alexander R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005002/
https://ncbi.nlm.nih.gov/pubmed/32029852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0732-8
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