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Benefit‐risk assessment of nivolumab 240 mg flat dose relative to 3 mg/kg Q2W regimen in Japanese patients with advanced cancers

Nivolumab 3 mg/kg every 2 weeks (Q2W) has been approved in Japan for various cancers; however, use of a flat dose is expected to simplify dosing and administration. A quantitative clinical pharmacology approach was used to assess the benefit‐risk profile of nivolumab 240 mg Q2W relative to the appro...

詳細記述

保存先:
書誌詳細
出版年:Cancer Sci
主要な著者: Bei, Di, Osawa, Mayu, Uemura, Shinji, Ohno, Tomoya, Gobburu, Jogarao, Roy, Amit, Hasegawa, Mayumi
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004547/
https://ncbi.nlm.nih.gov/pubmed/31773815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14252
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