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Assessment of nivolumab exposure and clinical safety of 480 mg every 4 weeks flat-dosing schedule in patients with cancer

BACKGROUND: A nivolumab monotherapy flat-dosing regimen of 480 mg every 4 weeks (Q4W) has been approved in several markets, including the United States, Canada, and European Union, as an alternative dosing regimen for several indications. Approvals of this Q4W regimen were based on population pharma...

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Bibliografski detalji
Izdano u:Ann Oncol
Glavni autori: Long, G V, Tykodi, S S, Schneider, J G, Garbe, C, Gravis, G, Rashford, M, Agrawal, S, Grigoryeva, E, Bello, A, Roy, A, Rollin, L, Zhao, X
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290887/
https://ncbi.nlm.nih.gov/pubmed/30215677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy408
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