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Benefit‐risk assessment of nivolumab 240 mg flat dose relative to 3 mg/kg Q2W regimen in Japanese patients with advanced cancers

Nivolumab 3 mg/kg every 2 weeks (Q2W) has been approved in Japan for various cancers; however, use of a flat dose is expected to simplify dosing and administration. A quantitative clinical pharmacology approach was used to assess the benefit‐risk profile of nivolumab 240 mg Q2W relative to the appro...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Bei, Di, Osawa, Mayu, Uemura, Shinji, Ohno, Tomoya, Gobburu, Jogarao, Roy, Amit, Hasegawa, Mayumi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004547/
https://ncbi.nlm.nih.gov/pubmed/31773815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14252
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