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Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer

Cellular senescence is historically regarded as a tumor suppression mechanism to prevent damaged cells from aberrant proliferation in benign and premalignant tumors. However, recent findings have suggested that senescent cells contribute to tumorigenesis and age‐associated pathologies through the se...

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Publicat a:Cancer Sci
Autors principals: Loo, Tze Mun, Miyata, Kenichi, Tanaka, Yoko, Takahashi, Akiko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004529/
https://ncbi.nlm.nih.gov/pubmed/31799772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14266
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