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Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death

The intracellular parasite Toxoplasma gondii resides inside a vacuole, which shields it from the host’s intracellular defense mechanisms. The cytokine interferon gamma (IFNγ) upregulates host cell effector pathways that are able to destroy the vacuole, restrict parasite growth and induce host cell d...

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Bibliographic Details
Published in:Curr Opin Microbiol
Main Authors: Saeij, Jeroen P, Frickel, Eva-Maria
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004510/
https://ncbi.nlm.nih.gov/pubmed/29141239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2017.10.021
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