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Recent advances in the development of integrase inhibitors for HIV treatment

PURPOSE OF THE REVIEW: The complex multistep life-cycle of HIV allows it to proliferate within the host and integrate its genome in to the host chromosomal DNA. This provirus can remain dormant for an indefinite period. The process of integration, governed by integrase (IN), is highly conserved acro...

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Publicat a:Curr HIV/AIDS Rep
Autors principals: Trivedi, Jay, Mahajan, Dinesh, Jaffe, Russell J., Acharya, Arpan, Mitra, Debashis, Byrareddy, Siddappa N.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004278/
https://ncbi.nlm.nih.gov/pubmed/31965427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11904-019-00480-3
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