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Recent advances in the development of integrase inhibitors for HIV treatment

PURPOSE OF THE REVIEW: The complex multistep life-cycle of HIV allows it to proliferate within the host and integrate its genome in to the host chromosomal DNA. This provirus can remain dormant for an indefinite period. The process of integration, governed by integrase (IN), is highly conserved acro...

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Detalles Bibliográficos
Publicado en:Curr HIV/AIDS Rep
Main Authors: Trivedi, Jay, Mahajan, Dinesh, Jaffe, Russell J., Acharya, Arpan, Mitra, Debashis, Byrareddy, Siddappa N.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004278/
https://ncbi.nlm.nih.gov/pubmed/31965427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11904-019-00480-3
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