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Recent advances in the development of integrase inhibitors for HIV treatment

PURPOSE OF THE REVIEW: The complex multistep life-cycle of HIV allows it to proliferate within the host and integrate its genome in to the host chromosomal DNA. This provirus can remain dormant for an indefinite period. The process of integration, governed by integrase (IN), is highly conserved acro...

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Bibliographic Details
Published in:Curr HIV/AIDS Rep
Main Authors: Trivedi, Jay, Mahajan, Dinesh, Jaffe, Russell J., Acharya, Arpan, Mitra, Debashis, Byrareddy, Siddappa N.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004278/
https://ncbi.nlm.nih.gov/pubmed/31965427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11904-019-00480-3
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