Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast

The nuclear farnesoid X receptor (FXR) and the enzyme soluble epoxide hydrolase (sEH) are validated molecular targets to treat metabolic disorders such as non‐alcoholic steatohepatitis (NASH). Their simultaneous modulation in vivo has demonstrated a triad of anti‐NASH effects and thus may generate s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Schierle, Simone, Helmstädter, Moritz, Schmidt, Jurema, Hartmann, Markus, Horz, Maximiliane, Kaiser, Astrid, Weizel, Lilia, Heitel, Pascal, Proschak, Anna, Hernandez‐Olmos, Victor, Proschak, Ewgenij, Merk, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004070/
https://ncbi.nlm.nih.gov/pubmed/31670489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900576
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados