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Refinement of inducible gene deletion in embryos of pregnant mice

CreERT2‐mediated gene recombination is widely applied in developmental biology research. Activation of CreERT2 is typically achieved by injection of tamoxifen in an oily vehicle into the peritoneal cavity of mid‐gestation pregnant mice. This can be technically challenging and adversely impacts welfa...

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Detalhes bibliográficos
Publicado no:Birth Defects Res
Main Authors: Savery, Dawn, Maniou, Eirini, Culshaw, Lucy H., Greene, Nicholas D. E., Copp, Andrew J., Galea, Gabriel L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003956/
https://ncbi.nlm.nih.gov/pubmed/31793758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdr2.1628
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