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Comparative genome‐scale analysis of Pichia pastoris variants informs selection of an optimal base strain

Komagataella phaffii, also known as Pichia pastoris, is a common host for the production of biologics and enzymes, due to fast growth, high productivity, and advancements in host engineering. Several K. phaffii variants are commonly used as interchangeable base strains, which confounds efforts to im...

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Publicado en:Biotechnol Bioeng
Main Authors: Brady, Joseph R., Whittaker, Charles A., Tan, Melody C., Kristensen, D. Lee, Ma, Duanduan, Dalvie, Neil C., Love, Kerry Routenberg, Love, J. Christopher
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003935/
https://ncbi.nlm.nih.gov/pubmed/31654411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27209
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