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Systematic Single-Cell Analysis of Pichia pastoris Reveals Secretory Capacity Limits Productivity
Biopharmaceuticals represent the fastest growing sector of the global pharmaceutical industry. Cost-efficient production of these biologic drugs requires a robust host organism for generating high titers of protein during fermentation. Understanding key cellular processes that limit protein producti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369916/ https://ncbi.nlm.nih.gov/pubmed/22685548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037915 |
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