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Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes

Homing based gene drives (HGD) possess the potential to spread linked cargo genes into natural populations and are poised to revolutionize population control of animals. Given that host encoded genes have been identified that are important for pathogen transmission, targeting these genes using guide...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Kandul, Nikolay P., Liu, Junru, Buchman, Anna, Gantz, Valentino M., Bier, Ethan, Akbari, Omar S.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003086/
https://ncbi.nlm.nih.gov/pubmed/31882406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400985
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