Efficient allelic-drive in Drosophila

Gene-drive systems developed in several organisms result in super-Mendelian inheritance of transgenic insertions. Here, we generalize this “active genetic” approach to preferentially transmit allelic variants (allelic-drive) resulting from only a single or a few nucleotide alterations. We test two c...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Guichard, Annabel, Haque, Tisha, Bobik, Marketta, Xu, Xiang-Ru S., Klanseck, Carissa, Kushwah, Raja Babu Singh, Berni, Mateus, Kaduskar, Bhagyashree, Gantz, Valentino M., Bier, Ethan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456580/
https://ncbi.nlm.nih.gov/pubmed/30967548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09694-w
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