Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to generate gene-drive systems capable of introgressing the genes throughout wild vector populations. We developed a highly effective autonomou...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gantz, Valentino M., Jasinskiene, Nijole, Tatarenkova, Olga, Fazekas, Aniko, Macias, Vanessa M., Bier, Ethan, James, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679060/
https://ncbi.nlm.nih.gov/pubmed/26598698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521077112
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