Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to generate gene-drive systems capable of introgressing the genes throughout wild vector populations. We developed a highly effective autonomou...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gantz, Valentino M., Jasinskiene, Nijole, Tatarenkova, Olga, Fazekas, Aniko, Macias, Vanessa M., Bier, Ethan, James, Anthony A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679060/
https://ncbi.nlm.nih.gov/pubmed/26598698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521077112
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