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Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia

Glycogen storage disease type Ia (GSD Ia) is caused by autosomal mutations in glucose-6-phosphatase α catalytic subunit (G6PC) and can present with severe hypoglycemia, lactic acidosis and hypertriglyceridemia. In both children and adults with GSD Ia, there is over-accumulation of hepatic glycogen a...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Yavarow, Zollie A, Kang, Hye-Ri, Waskowicz, Lauren R, Bay, Boon-Huat, Young, Sarah P, Yen, Paul M, Koeberl, Dwight D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003036/
https://ncbi.nlm.nih.gov/pubmed/31816064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz290
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