A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia

Background: Glycogen storage disease type Ia (GSD Ia), also known as von Gierke disease, is the most common glycogen storage disorder. It is caused by the deficiency of glucose-6-phosphatase, the enzyme that catalyzes the final step of gluconeogenesis and glycogenolysis. The accumulation of glucose-...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Zhou, Jin, Waskowicz, Lauren R., Lim, Andrea, Liao, Xiao-Hui, Lian, Brian, Masamune, Hiroko, Refetoff, Samuel, Tran, Brian, Koeberl, Dwight D., Yen, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707038/
https://ncbi.nlm.nih.gov/pubmed/31337282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0007
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