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Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia

Glucose-6-phosphatase α (G6Pase) deficiency, also known as von Gierke’s Disease or Glycogen storage disease type Ia (GSD Ia), is characterized by decreased ability of the liver to convert glucose-6-phosphate to glucose leading to glycogen accumulation and hepatosteatosis. Long-term complications of...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Principais autores: Waskowicz, Lauren R, Zhou, Jin, Landau, Dustin J, Brooks, Elizabeth D, Lim, Andrea, Yavarow, Zollie A, Kudo, Tsubasa, Zhang, Haoyue, Wu, Yajun, Grant, Stuart, Young, Sarah P, Huat, Bay Boon, Yen, Paul M, Koeberl, Dwight D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298237/
https://ncbi.nlm.nih.gov/pubmed/30256948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy343
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