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Combined burden and functional impact tests for cancer driver discovery using DriverPower

The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a sof...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Shuai, Shimin, Gallinger, Steven, Stein, Lincoln D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002750/
https://ncbi.nlm.nih.gov/pubmed/32024818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13929-1
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