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Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
The type and genomic context of cancer mutations depend on their causes. These causes have been characterized using signatures that represent mutation types that co-occur in the same tumours. However, it remains unclear how mutation processes change during cancer evolution due to the lack of reliabl...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002414/ https://ncbi.nlm.nih.gov/pubmed/32024834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14352-7 |
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