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Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine
Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how cancers develop and respond to treatment. Subclonal reconstruction methods cluster mutations into groups that co-occur within the same subpopula...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845980/ https://ncbi.nlm.nih.gov/pubmed/33465079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008400 |
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