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Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine
Tumors contain multiple subpopulations of genetically distinct cancer cells. Reconstructing their evolutionary history can improve our understanding of how cancers develop and respond to treatment. Subclonal reconstruction methods cluster mutations into groups that co-occur within the same subpopula...
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| Publicado en: | PLoS Comput Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845980/ https://ncbi.nlm.nih.gov/pubmed/33465079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008400 |
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