Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

β-thalassemia [β-Thal] is caused by defective β-globin production leading to globin chain imbalance, aggregation of free alpha chain in developing erythroblasts, reticulocytes, and mature circulating red blood cells. The hypochromic thalassemic red cells exhibit increased cell dehydration in associa...

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Detalhes bibliográficos
Publicado no:Blood Cells Mol Dis
Main Authors: Shmukler, Boris E., Rivera, Alicia, Bhargava, Parul, Nishimura, Katherine, Kim, Edward H., Hsu, Ann, Wohlgemuth, Jay G., Morton, James, Snyder, L. Michael, De Franceschi, Lucia, Rust, Marco B., Hubner, Christian A., Brugnara, Carlo, Alper, Seth L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002294/
https://ncbi.nlm.nih.gov/pubmed/31835175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2019.102389
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