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Osteoclasts Derive Predominantly from Bone Marrow-Resident CX(3)CR1(+) Precursor Cells in Homeostasis While Circulating CX(3)CR1(+) Cells Contribute to Osteoclast Development During Fracture Repair

Osteoclasts (OC) originate from either bone marrow (BM)-resident or circulating myeloid OC progenitors (OCP), expressing the receptor CX(3)CR1. Multiple lines of evidence argue that OCP in homeostasis and inflammation differ. We investigated the relative contributions of bone marrow-resident and cir...

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書誌詳細
出版年:J Immunol
主要な著者: Novak, Sanja, Roeder, Emilie, Kalinowski, Judith, Jastrzebski, Sandra, Aguila, Hector L., Lee, Sun-Kyeong, Kalajzic, Ivo, Lorenzo, Joseph A.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002248/
https://ncbi.nlm.nih.gov/pubmed/31915261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900665
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