Osteoclasts Derive Predominantly from Bone Marrow-Resident CX(3)CR1(+) Precursor Cells in Homeostasis While Circulating CX(3)CR1(+) Cells Contribute to Osteoclast Development During Fracture Repair

Osteoclasts (OC) originate from either bone marrow (BM)-resident or circulating myeloid OC progenitors (OCP), expressing the receptor CX(3)CR1. Multiple lines of evidence argue that OCP in homeostasis and inflammation differ. We investigated the relative contributions of bone marrow-resident and cir...

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Vydáno v:J Immunol
Hlavní autoři: Novak, Sanja, Roeder, Emilie, Kalinowski, Judith, Jastrzebski, Sandra, Aguila, Hector L., Lee, Sun-Kyeong, Kalajzic, Ivo, Lorenzo, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002248/
https://ncbi.nlm.nih.gov/pubmed/31915261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900665
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