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Osteoclasts Derive Predominantly from Bone Marrow-Resident CX(3)CR1(+) Precursor Cells in Homeostasis While Circulating CX(3)CR1(+) Cells Contribute to Osteoclast Development During Fracture Repair
Osteoclasts (OC) originate from either bone marrow (BM)-resident or circulating myeloid OC progenitors (OCP), expressing the receptor CX(3)CR1. Multiple lines of evidence argue that OCP in homeostasis and inflammation differ. We investigated the relative contributions of bone marrow-resident and cir...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002248/ https://ncbi.nlm.nih.gov/pubmed/31915261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900665 |
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