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Synthesis of Tri- and Difluoromethoxylated Compounds by Visible Light Photoredox Catalysis

The trifluoromethoxy (OCF(3)) and difluoromethoxy (OCF(2)H) groups are fluorinated structural motifs that exhibit unique physicochemical characteristics. Incorporation of these substituents into organic molecules is a highly desirable approach used in medicinal chemistry and drug discovery processes...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Lee, Johnny W., Lee, Katarzyna N., Ngai, Ming-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001783/
https://ncbi.nlm.nih.gov/pubmed/30943329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902243
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