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Synthesis of Tri- and Difluoromethoxylated Compounds by Visible Light Photoredox Catalysis
The trifluoromethoxy (OCF(3)) and difluoromethoxy (OCF(2)H) groups are fluorinated structural motifs that exhibit unique physicochemical characteristics. Incorporation of these substituents into organic molecules is a highly desirable approach used in medicinal chemistry and drug discovery processes...
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| Publié dans: | Angew Chem Int Ed Engl |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7001783/ https://ncbi.nlm.nih.gov/pubmed/30943329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902243 |
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