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Differential sorting behavior for soluble and transmembrane cargoes at the trans-Golgi network in endocrine cells

Regulated secretion of neuropeptides and peptide hormones by secretory granules (SGs) is central to physiology. Formation of SGs occurs at the trans-Golgi network (TGN) where their soluble cargo aggregates to form a dense core, but the mechanisms controlling the sorting of regulated secretory cargoe...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Hummer, Blake H., Maslar, Drew, Soltero-Gutierrez, Margarita, de Leeuw, Noah F., Asensio, Cedric S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001476/
https://ncbi.nlm.nih.gov/pubmed/31825717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-10-0561
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