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HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification

Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are still not completely understood. Recent studie...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Hummer, Blake H., de Leeuw, Noah F., Burns, Christian, Chen, Lan, Joens, Matthew S., Hosford, Bethany, Fitzpatrick, James A. J., Asensio, Cedric S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739301/
https://ncbi.nlm.nih.gov/pubmed/29074564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0491
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