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Upregulation of PUM1 Expression in Preeclampsia Impairs Trophoblast Invasion by Negatively Regulating the Expression of the lncRNA HOTAIR

Pumilio (PUM) proteins are members of a highly conserved RNA-binding protein family that posttranscriptionally regulate gene expression in many organisms. However, their roles in the placenta are unclear. In the present study, we report the requirement for the PUM homolog 1 (PUM1) gene in preeclamps...

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Библиографические подробности
Опубликовано в: :Mol Ther
Главные авторы: Zhang, Yan, He, Xiao-Ying, Qin, Shi, Mo, Hui-Qin, Li, Xiao, Wu, Fan, Zhang, Jing, Li, Xing, Mao, Lin, Peng, Ya-Qing, Guo, Yu-Na, Lin, Yi, Tian, Fu-Ju
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001091/
https://ncbi.nlm.nih.gov/pubmed/31862314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.025
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