Upregulation of PUM1 Expression in Preeclampsia Impairs Trophoblast Invasion by Negatively Regulating the Expression of the lncRNA HOTAIR

Pumilio (PUM) proteins are members of a highly conserved RNA-binding protein family that posttranscriptionally regulate gene expression in many organisms. However, their roles in the placenta are unclear. In the present study, we report the requirement for the PUM homolog 1 (PUM1) gene in preeclamps...

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Pubblicato in:Mol Ther
Autori principali: Zhang, Yan, He, Xiao-Ying, Qin, Shi, Mo, Hui-Qin, Li, Xiao, Wu, Fan, Zhang, Jing, Li, Xing, Mao, Lin, Peng, Ya-Qing, Guo, Yu-Na, Lin, Yi, Tian, Fu-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001091/
https://ncbi.nlm.nih.gov/pubmed/31862314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.025
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