Upregulation of PUM1 Expression in Preeclampsia Impairs Trophoblast Invasion by Negatively Regulating the Expression of the lncRNA HOTAIR

Pumilio (PUM) proteins are members of a highly conserved RNA-binding protein family that posttranscriptionally regulate gene expression in many organisms. However, their roles in the placenta are unclear. In the present study, we report the requirement for the PUM homolog 1 (PUM1) gene in preeclamps...

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Publicado en:Mol Ther
Autores principales: Zhang, Yan, He, Xiao-Ying, Qin, Shi, Mo, Hui-Qin, Li, Xiao, Wu, Fan, Zhang, Jing, Li, Xing, Mao, Lin, Peng, Ya-Qing, Guo, Yu-Na, Lin, Yi, Tian, Fu-Ju
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001091/
https://ncbi.nlm.nih.gov/pubmed/31862314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.025
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