Upregulation of PUM1 Expression in Preeclampsia Impairs Trophoblast Invasion by Negatively Regulating the Expression of the lncRNA HOTAIR

Pumilio (PUM) proteins are members of a highly conserved RNA-binding protein family that posttranscriptionally regulate gene expression in many organisms. However, their roles in the placenta are unclear. In the present study, we report the requirement for the PUM homolog 1 (PUM1) gene in preeclamps...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Zhang, Yan, He, Xiao-Ying, Qin, Shi, Mo, Hui-Qin, Li, Xiao, Wu, Fan, Zhang, Jing, Li, Xing, Mao, Lin, Peng, Ya-Qing, Guo, Yu-Na, Lin, Yi, Tian, Fu-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001091/
https://ncbi.nlm.nih.gov/pubmed/31862314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.025
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