Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Regulatory T cells (Tregs) subdue immune responses. Central to Treg activation are changes in lipid metabolism that support their survival and function. Fatty acid binding proteins (FABPs) are a family of lipid chaperones required to facilitate uptake and intracellular lipid trafficking. One family...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Field, Cameron S., Baixauli, Francesc, Kyle, Ryan L., Puleston, Daniel J., Cameron, Alanna M., Sanin, David E., Hippen, Keli L., Loschi, Michael, Thangavelu, Govindarajan, Corrado, Mauro, Edwards-Hicks, Joy, Grzes, Katarzyna M., Pearce, Edward J., Blazar, Bruce R., Pearce, Erika L.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001036/
https://ncbi.nlm.nih.gov/pubmed/31883840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.11.021
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