Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b

The explosive spread of Zika virus (ZIKV) has been associated with major variations in severe disease and congenital afflictions among infected populations, suggesting an influence of host genes. We investigated how genome-wide variants could impact susceptibility to ZIKV infection in mice. We first...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Manet, Caroline, Simon-Lorière, Etienne, Jouvion, Grégory, Hardy, David, Prot, Matthieu, Conquet, Laurine, Flamand, Marie, Panthier, Jean-Jacques, Sakuntabhai, Anavaj, Montagutelli, Xavier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000970/
https://ncbi.nlm.nih.gov/pubmed/31694939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01034-19
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg