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A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation
IκB kinase 2 (IKK2) is well known for its pivotal role as a mediator of the canonical NF-κB pathway, which has important functions in inflammation and immunity, but also in cancer. Here we identify a novel and critical function of IKK2 and its co-factor NEMO in the activation of oncogenic c-Jun N-te...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7000802/ https://ncbi.nlm.nih.gov/pubmed/32019925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14502-x |
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